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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '038d16ce22699f3a82f00d97a22238e8aa6f639e555a65db3dc22bee9916e8f6' 
  AND token = 'bzZGDsim6VHbcNhVI5GJAEBP+DPMt0MRqRnC27H6cxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}