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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1c0a400894c1a6a80b55c198363fc401954cbf8dd8222f4ed8321d6dcb0c26' 
  AND token = '9PoigamsL4psAJJVhdgXV3qe49xXf7kxCjkmSHkZEsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}