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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a156ed33ee57ba33e7a69dd02b8d93eaa79ee01bb95bbda876d50859c13555' 
  AND token = 'K/ytjGwkMduM1jO2Ori6QC1kxMpiwKD9AhoFdd7I0Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}