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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb83e9583c63193c7c681cb10ce151762ec8b0d28f83e45ac491dbab2c12897c' 
  AND token = 'S0mMjoaZXauxUn/P69mw6GtbFaOPCTI9rWuYx+yhiVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}