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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32444948cd7b37d08c866a14705d3e8d68a1ea9a3fbf9ef479ec6730a0befb09' 
  AND token = 'D+b0Gc4Wgx5vzSYH5k61Y09/EIqPELGM+z53ae39Eg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}