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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00d51b9e23656637230bd0d5712eddb39dce7a9f16e766dcc7ae1a1b5769ef9' 
  AND token = '1syuUvPLdBRixp1EPpLUM+8tTJWCSu2ZOe2Ti10Pi7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}