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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0c33145d885f1360fcf15231ab13e69e6162157d769067d5ca115ff120090ad' 
  AND token = 'in4MwgSrsF19uGbRVky1EYr1mDke9m2LewAfL/4ra+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}