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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c628ee0f05818bc02744341e022382bd253a201e2f2ee02e1fe717b5041b1380' 
  AND token = 'dw75pYvTU+D+KGVrsUjDi5IxzSGy7ayeZM1KsPAYNUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}