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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37fa35e0d9753b038b20b5bdd9707e36bf7f27ffe316ccc4359a85665e20019a' 
  AND token = 'dhgJrrdUFjs/lNQLPXfnYq0LiUlPcnureLjHhvT3yZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}