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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6323c299f8bf73ee3f5481905fd0049d65c988688c5889394adb660297695645' 
  AND token = 'oj622uFPEmxdr2iFEPC+XacmQV01rnC9cfWCzCU9cyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}