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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f1dd98901fa6cb5060100a1645774e0c636207be06e1b9fb937de8cac7cd5b' 
  AND token = 'OKSMic+3Jd5Fd1lQcb06D/lvnZobXQ5ve3ddG6g/i+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}