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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2259e88cec5a9fbbbbc9354124827750c68700e9ee11fa1980e3284eca0749' 
  AND token = '9udaXL7uf5EYV5ZZxcSJ4NrR5U0pbZvghSlY9/yKK0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}