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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2145f977cb0f18e958198a5e0f4edd32814e5654e384986ed1c8570defb756b3' 
  AND token = '5EtHud7sJ0TI236K7vgpSWbCfcm+ZvXNtJf7wgqYaFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}