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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e42ec681102efde2f9e336b957398dbb550f8e7ed1b483b594cde5f2a163667' 
  AND token = '+DUDnmhD2d27wq2S9y6rqVOB7mN2YEcNBBfWAgoH6c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}