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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aed26d9eb4a52227af69733491ab2d2d199d6327fbd7a9513886779da3ed3d1' 
  AND token = 'SW0jNycZFBuhO02RUHxW5LEpW3ZStsjkChrni+E91lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}