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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d4ded7495a5e68410f81a3064673a77393e8844eb924df1d4fc39c68ed8fdc' 
  AND token = 'Hnun1GUXZncWEXcILpAOmVAwcKAj3o3SsGDl0HJk1CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}