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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf357fbfa160cd065aa6c41af52054d3a0c407d30e732e2b0195b9108e2f02d' 
  AND token = 'H762FOK1JhlmE6MLxOLGNXxoOh60GCXVyceR9HOhfQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}