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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e58e8eb26c5412d87879f09cec297214397558d702aa31d226c2c5455766e0a' 
  AND token = 'Xqj4felAkPYhgl7iyX3QLsy9FaJBjCuIqVxjqOzfOd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}