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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2eeb57cc4ff6962f694b13b763d03fa901c08d39173ff72cd7056d4e8b09e8' 
  AND token = 'RBjjaFEQIBWisVtr7ZbMkTv/4tIxoJBNljSsN7WzoRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}