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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc65c82ebde6c1c12319d60edfc1d90bf9d60cf016da5c8d7d524e0d1630854' 
  AND token = '+lsfSCDY+PX/BzonZZzMlk+WQJOP2v5xLDBO+/qKTaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}