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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0290ce98b88f99a67e1274cf7e65561ab1c8d92eef02d12d520d45cabd94cd3c' 
  AND token = 'jGkWEIa/NdgSSRf2/tAVj5tcneVzbHrPX+j+Zas98qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}