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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c396675416ca44469feb8a6d30ddf9bd238b1d1130a43e3c5a46e10403f6c82' 
  AND token = 'vkwjwoDgic9AFpZ4KEw/zVgo/A7Y7xjto5encT4Qiec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}