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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2efed5dd922b8983730f04213b009757fac975f4204d16a7acdb8843373ccc80' 
  AND token = 't5yPn0j2dDroj4Sqq1z60LlUomwYMfmmtwpHabdi+m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}