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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c46a285937bfe1e69198c919ee9389b76d6e69d767e10532fde956b8546e1e' 
  AND token = 'e2g5NkefWpOiLk+wHjn5LFANg1XeqtCtUJVpzcxGHb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}