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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7f6093f323a40141b5f569a95955dd79454bf328c8a57ca4082a8792c8e621' 
  AND token = 'yM5AZod7Im8pdXutZu55eVebTygajYsAnWK4rc+0Oz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}