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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5986b53b7e6f20c921c40e270b4cc579babed9c1b9d26be11a2b122cc34d5f' 
  AND token = '3wfe5XWqfqAveW0xA5iB2AotAaxx85tCeRAfuWfTlGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}