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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1205f238acdb6e63f2717280357f451378604c63a4469dfd4e91267128c0e027' 
  AND token = 'WcphsVe026YvBrvkhptZNpi/Wz/m9pTdEtTayg9dMdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}