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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca36d13d601af1ce05a030bc30cfe2332687f73d8cceb18d896caa805f88f7ec' 
  AND token = 'j2hI/HoL2ZEB+U8/ITU7ctgds8QNitwIPQ8n12AQqwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}