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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd70dc1e3b9a2565db3b520161a0008f7f035c284351bbe2be001e14c0e5164de' 
  AND token = 'D+pm4ZEN5tLdnqsmDnu/sQ3W48Rm9hf0PMLxM4vF1D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}