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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f82345d5e30231bbd883563561d1c30f811e16701b8ca237d8ae8eaf43dd867' 
  AND token = '0h4KYKzxh01/hJ72U4P4Rpu+WLZ1+DiagByQ3G02D5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}