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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18466105b9429eda5b0eb6f87335a60b3e3a51d74ff9edfe2cede3e718e4088b' 
  AND token = 'xx9DIUJsyMy7y285GMDgyAOZq7/nhU88SE64JRVUYa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}