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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b9f700ec2b1c7c67fac1d6e7aae15cf19e07b586f3676134dbe742ebbf861b' 
  AND token = '2O+iDFVMeBh+r7rpmZqA4e15PxDfQhpzFbZSim0q7BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}