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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03a596b65bf9c9696cf66374019cc775801ff61b69f0b8c91e27cddf7b24da0e' 
  AND token = 'qHtYw7cnaXdXoRnQzfFVoPCMyuvMKDqlO/N9jcH1Pck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}