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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd008c50f48d9d837644c8d45c2288d7234be38da4f2fb956e17c27a25348bff' 
  AND token = 'KTJBB49+04K2Aig1qjb4o5jw3Aytarxup5i5iRUN0OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}