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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a02f4df91c3db8a29de8d32fef2f69a751364cf709bc3042f220dcfe96f138' 
  AND token = 'gSUawQ5A8/YY/DNSEarIfasUX9gT0eZG8TJ3jSlPXkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}