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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c1157f731b8cf9aaa3aca9511937cceb841250c3eaca87146d6640c9f322ab' 
  AND token = '2jazXYOeSA8IDSgIryKk6Z7UpBuGXG0ZjaroVF04ZBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}