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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f73effc84433449bb8cd4205d68d4e9d10768987cd7c910cdd1c0576569a4e3' 
  AND token = 'Rm/Tne/QxQMuqsptBIHp/dBgS/sE0UJQKopwp3lo/GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}