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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b8de49683cd2416edaf4216264049f1aa2b5e0cf567ee184ccf363d7e3cfeb' 
  AND token = 'xKbbtNaheZFD1Vo0FAQ3T/FzNN+Vpr2of1TXJcnB3HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}