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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e003bcb4c31ab90b231409e131738b418ca44495db87cccb21f36134ddbfd842' 
  AND token = 'FhQCQJgQzzF68UXsvb+oUk9L15EJRJoi/g4o5Kfz6n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}