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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2e4363320d8f3d334e0ab1714a745a44f144859316df1e04caa0db51015cca' 
  AND token = 'F5g8/h2XHiuIgtue9SieCKkeFDxZzMygJDTjcC1Y1Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}