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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1645927fd88426aad777961027c9f8b50c96bc31675c83d7e5f3c373bed8eb' 
  AND token = 'fTPmSknm7wAMsL6HQOyNztaag2ZOtX+XsgkWmwsp+KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}