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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a1c684114551da49d0b4ba3b590d438fa1aedd0b67997912c7883f3f49b409' 
  AND token = 'Z94zgsdZexV7ZHpNo9HMd1vjFLeLUF8uKlhpBHp7OQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}