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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33c9a2e6e62a6f35875f9e80055b06a075306bbdc342d72cf3ea72acaf0649d' 
  AND token = 'jZ8SgLxD0Ab5enfzmYVWH3COhABo8fDHHL69Urx5Lqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}