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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2620fc3ddbf6039554ebf4adc2ff7b05f5ec3dd49e2773beec01251f060289a' 
  AND token = 'vHUkBS1uGT6L9bZpbEYdYZF3eDSPHO3P2fkLEzhQEsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}