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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c0d88652dd45f7858e408e378058cb5e713288d5151a55f49e6d457d35a7f7' 
  AND token = 'QNaz9J1S/GYzP3SuQirjCpA5cMfMyREZI2sb4EPzJ28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}