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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4e76018ae18d0a462eb5562d2fe09056e369f39994278c73cd4e7628dfaa4b' 
  AND token = 'XQ+379M9JSXwbHguQSmA9tpqqPDekn4nL0B0iyfyYC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}