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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254270e31c13b221cc76731fe02c8367626a33c3932177038b0fc245e2a8ee12' 
  AND token = 'cMR6xdEtX+OkuAqgGDgk0dFlSMUlynOs+tICNGmso18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}