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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15105df1fedc1e76146ceed00c0b12de3ed0d8773db0d5ab11b1f65f3698349a' 
  AND token = 'L6NRJAK3eKK2JkbQ0vjhGGSDqctNFepFj39p+hUSXKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}