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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a9883b677244147eade672813f634b86c8650683de4e8f72ec7d5a1b716cb1' 
  AND token = 's5VW5Pkt6Q0yVNQI4B+hk5k17AxrvZzVtksnreia1oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}