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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a4464b41a81243f0b020356db23dfbb89d3b6016707a7516d61a980347456b' 
  AND token = 's0v3w5oDj0tAJAulRV3TKhzOowp+KcpP6Jv0Mf+GP1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}